Having been recently dumped for the nineteenth time by a girl named Katherine, recent high school graduate and former child prodigy Colin sets off on a road trip with his best friend to try to find some new direction in life while also trying to create a mathematical formula to explain his relationships.
Cameron Smith, a disaffected sixteen year-old who, after being diagnosed with Creutzfeldt-Jakob (aka mad cow) disease, sets off on a road trip with a death-obsessed video gaming dwarf he meets in the hospital in an attempt to find a cure.
When Rafe Kane enters middle school, he teams up with his best friend, "Leo the Silent," to create a game to make school more fun by trying to break every rule in the school's code of conduct.
After his hippie grandmother ends up in the hospital, Cap Anderson is forced to leave the commune where he is homeschooled and attend Claverage Middle School, where his odd looks and behavior make him the target of bullies.
When high school sophomore Jessie's long-term best friend transforms herself into a punk and goes after Jessie's would-be boyfriend, Jessie decides to visit "the wild nerd yonder" and seek true friends among classmates who play Dungeons and Dragons.
The adventures of Arthur Dent as he makes his way through the galaxy after being plucked off the earth seconds before it is destroyed to make way for a galactic freeway.
Seventeen-year-old Greg has managed to become part of every social group at his Pittsburgh high school without having any friends, but his life changes when his mother forces him to befriend Rachel, a girl he once knew in Hebrew school who has leukemia.
In her first year at a suburban New Jersey high school, Mary Elizabeth Cep, who now calls herself "Lola," sets her sights on the lead in the annual drama production, and finds herself in conflict with the most popular girl in school.
Seventeen-year-old Vince's life is constantly complicated by the fact that he is the son of a powerful Mafia boss, a relationship that threatens to destroy his romance with the daughter of an FBI agent.
Budding cartoonist Junior leaves his troubled school on the Spokane Indian Reservation to attend an all-white farm town school where the only other Indian is the school mascot.
While navigating his first year of high school and awaiting the birth of his new baby brother, Scott loses old friends and gains some unlikely new ones as he hones his skills as a writer.
Eighteen-year-old Ash wants nothing to do with senior prom, but when disaster strikes and her desperate friend, Nat, needs her help to get it back on track, Ash's involvement transforms her life.